PIM3 and type 1 diabetes mellitus: We also replicated a shared locus near HORMAD2 between CDTA and type 1 diabetes, and extend IBD-associated83 CDTA loci to SLC45A1 and PIM3. Beyond specific loci, we reported enrichment of CDTA-associated variants in 10 out of 16 genes involved with the TNFR2 pathway, and many intracellular genes of the canonical NFκB pathway84.