In univariate optimism-corrected analysis, high cancer cell PD-L2 was a strong predictor of PFS (HR, 2.5; 95% CI, 1.4 to 2.9; P = .003; Fig 3), whereas stromal cell PD-L2 was somewhat weaker predictor of PFS (HR, 1.9; 95% CI, 1.1 to 3.3; P = .030). Here, PDCD1LG2 is linked to cancer.