TAPT1 and malaria: In Plasmodium falciparum, the causative pathogen for malaria, mutations in TAPT1's homolog, pfcarl, confer resistance to various structurally unrelated antimalarial compounds which appear to target the ER/Golgi function of the parasite (Meister et al, 2011; Kuhen et al, 2014; LaMonte et al, 2016).