CRP and major depressive disorder: Specifically, we observed consistent genetic correlations between our female-specific GWASs from the UKB and other both-sex combined GWASs (MVP-UKB depression = 0.81, MVP-UKB anxiety = 0.72, and CHARGE-UKB C-reactive protein [CRP] = 0.99) (Figure 2B; eTable 5 in Supplement 1).