However, even though NRP1 seemed essential for virus infection in this study, a previous study showed that SARS-CoV-2 D614G infection in primary and human inducible pluripotent stem cell derived (hPSC) cortical astrocytes, also lacking ACE2, was dependent on DPP4 and CD147 but not NRP1 (35). This evidence concerns the gene NRP1 and infection.