Interestingly, YBX1 is also one of the genes whose gene-protein expression is the most correlated in cancers vs. normal tissues (Kosti et al., 2016), and YBX1 was identified among the few genes in a clustered regularly interspaced short palindromic repeats (CRISPR) screen showing the highest sensitivities with broad proteome co-expression in cancer cell lines (Nusinow et al., 2020, Figure S4 of this reference), pointing toward a possible role for YBX1 in cancer. This evidence concerns the gene YBX1 and cancer.