Therefore, as a consequence of abnormal cell growth, GRP78/BiP can ultimately present on the cell surface of numerous cell types (Table 1) including, lymphoma, neuroblastoma, lymphoblastic leukaemia, ovarian tumour, lung and colon adenocarcinoma.81, 82, 83, 84, 85. This evidence concerns the gene HSPA5 and colon adenocarcinoma.