AFP and neoplasm: Importantly, in the GSE14520 cohort, we noted that AFP (<=300 ng/ml), tumor size (<=5 cm) and non-multinodular were associated with the low-risk group, whereas AFP (>300 ng/ml), tumor size (>5 cm) and multinodular were mainly associated with the high-risk group (p < 0.05, Fig. 6C).