Categorical data are expressed as number and percentage and analyzed by the Chi-Square test. BMI body mass index, COPD chronic obstructive pulmonary disease, CCI Charlson Comorbidity Index, MNA-SF mini-nutritional assessment-short form, TUG timed up and go, HGS handgrip strength, 6 MW 6-meter walking, CKD chronic kidney disease, HgB hemoglobin, Hba1c glycated hemoglobin, LDL-C low-density lipoprotein cholesterol, eGFR estimated glomerular filtration rate, SU sulphonylurea, DPP4i dipeptidyl peptidase-4 inhibitors. This evidence concerns the gene DPP4 and chronic obstructive pulmonary disease.