IHC staining of pancreatic head and tumor sections showed that pERK (a KRAS activation effector), PCNA (a proliferative marker), CK19 (a ductal origin marker), E-cadherin (an epithelial lineage marker), and vimentin (a mesenchymal marker) were expressed in the tumor stroma (Fig. 6a, b), indicating that PDAC had developed in the DIC pig. Here, KRT19 is linked to neoplasm.