CD4 and Sepsis: Patients with sepsis in the high-risk group had lower ratios of plasma cell, T cells CD4 naive, T cells CD4 memory activated, natural killer (NK) cells resting, NK cells activated, macrophages M0, macrophages M2, eosinophils, monocytes mast cells activated and mast cells resting than those in the low-risk group (P < 0.05, Fig. 7a, b).