In addition, the sepsis patients in the high-risk group were characterized by upregulated expression of CD200R1 and leukocyte-associated immunoglobulin-like receptor 1, whereas the sepsis patients in the low-risk group were characterized by high expression of C10orf54, CD160, CD244, CD40, CD48, CD86, LAG3, TIGIT, TNFRSF14, TNFRSF25, TNFRSF8, TNFRSF9 and TNFSF14 (P < 0.05, Fig. 8b). The gene discussed is LAG3; the disease is Sepsis.