ELOVL3 and hepatocellular carcinoma: It also showed sarogliazar treatment causes up-regulation of genes involved in mitochondrial fatty acid beta-oxidation (Acot1, Acot3,), lipid metabolism (Fabp1), Bile acid/bile salt metabolism (Slc10a1) and alpha-linolenic acid (ALA) metabolism (Elovl3,) pathways (Fig. 5B), which are involved in prevention of HCC through induction of apoptosis, antioxidant activity, limiting the cell proliferation and inhibition of growth signal transduction.