In the clinical settings, given that both IHC and real-time PCR are routinely performed, our analysis suggests overexpression of MMP10 in 68/79 (86%) of patients with lymph node metastasis, whereas only 11/79 (14%) of patients with lymph node metastasis has low expression of MMP10 (chi-square value = 33.53, p-value < 0.00001). This evidence concerns the gene MMP10 and metastatic malignant neoplasm in the lymph nodes.