At 6 months postpartum in women who achieved ≥80% of postprandial targets in the tighter glycemic targets group, there was a 122.8% (95% CI 21.22 to 309.51, P = 0.01) increase in CRP concentrations, compared with those in the less tight glycemic targets group after adjustment for GA at OGTT, baseline values, ethnicity, BMI and history of GDM. This evidence concerns the gene CRP and gestational diabetes.