Gestational diabetes mellitus (GDM) is characterized by any degree of glucose intolerance with onset or recognition during pregnancy.1 The pathophysiology of GDM has been linked to dysregulation of inflammatory markers that interfere with the action of insulin,2 heightening the state of insulin resistance typically seen in pregnancy.3 There are known differences in the profile of cytokines and adipokines in women with GDM compared to pregnant women without GDM. The gene discussed is INS; the disease is gestational diabetes.