On the other hand, genes inversely correlated with activity scores point to the upregulation of genes involved in B cell and T cell receptor signalling (MALT1, PTPN6, NFATC2, MAP4K1, REL), EMT (ITGB4), fibroblast growth factor activity (KLB), fatty acid uptake/metabolism (FABP2, SUGCT, LTA4H), glucose utilisation (GNPDA1, NEUROD1, SCGN, SLC2A12, SH2D3A, PIK3C2G), DNA repair (BARD1), and gene biomarkers for hepatocellular carcinoma (HCC) (HELLS, PIWIL2, TROAP). The gene discussed is PTPN6; the disease is hepatocellular carcinoma.