YTHDF1 and neoplasm: Interestingly, tumor-intrinsic YTHDF1 deficiency significantly inhibited tumorigenesis in immunocompetent mice, as evidenced by a lower tumor volume (Fig. 2A), tumor weight (Fig. 2B), and luminescence intensity (Fig. 2C, D) and a favorable survival time (Fig. 2E) in the Ythdf1-KO group.