Using protein microarrays, mass spectrometry and RNA pull‐down assays, we observed that BC and the 3′UTR of IMPAD1 simultaneously interacted with the RNA binding proteins NCL, hnRNPD, RBM3, SF3B4 and IGF2BP1, whereas hnRNPK mainly bound to IMPAD1. The gene discussed is NUCLEOLIN; the disease is breast cancer.