In blood cancer patients, the cancer antigen protein-protein interaction network includes a slightly broader range of genes such as BAGE5, CTAGE1, GAGE1, MAGEC2 and SSX1, and a cytokine-dominated network includes numerous interferons (IFNA1-7-8, IFNB1) and numerous interleukins associated with tumour growth, progression and metastasis (IL1A, IL17F, IL19, IL22, IL23) [85, 86, 88–92], plus ARG1 and ARG2. The gene discussed is IL22; the disease is cancer.