Glycine is a nonessential amino acid that is involved in the maintenance of normal blood pressure through several mechanisms, including the following by contributing to glutathione synthesis and consequently to the reduction of excess aldehydes and free radicals, by promoting nitric oxide (NO) production, and by participating in the synthesis of elastin and collagen; thus, a deficiency of glycine leads to endothelial dysfunction, impaired availability of NO, and impaired aortic elasticity, resulting in the development of HTN [18–20]. The gene discussed is ELN; the disease is hypertensive disorder.