TYK2 and infection: A large GWAS study from HGI, including three genome-wide association meta-analyses comprising 49,562 COVID-19 patients from 46 studies in 19 countries, identified 13 human genomic loci associated with infection or severe COVID-19, including TYK2, DPP9, and FOXP4 which corresponded to previously documented associations with lung or autoimmune diseases and inflammatory disorders [36].