TYK2 and COVID-19: Results of a genetic study of 2244 critically ill patients with COVID-19 in intensive care units across the UK identified associations on chromosomes 12q24.13, 19p13.2, 19p13.3, and 21q22.1, revealed the genes with innate immunity (IFNAR2 and OAS) and host-driven lung inflammatory injury (DPP9, TYK2, and CCR2) [8].