This lncRNA targets the sodium calcium exchanger, SLC8A1, and its upregulation has been shown to increase interleukin 10 (IL-10) and decrease IL-1β, IL-6, transforming growth factor α, nitric oxide, inducible nitric oxide synthase and endothelial nitric oxide synthase in a mouse model of myocardial infarction [13]. The gene discussed is IL1B; the disease is myocardial infarction.