There are similarities in the occurrences of HLA-DRB1 alleles (-DRB1*12, -DRB1*09, -DRB1*04, -DRB1*08, -DRB1*15, -DRB1*07, and -DRB1*14) in patients with NPC in our study compared with the results of authors around the world. Here, HLA-DRB1 is linked to nasopharyngeal carcinoma.