Peripheral myeloid DCs and pDCs in MM patients were also characterized by the downregulated expression of CCR5, CCR7, DEC-205, HLA-DR, and co-stimulatory molecules, and a defective IFN-γ production, associated with impaired T cell [97,98] proliferation and activation which impair their migration and antigen-uptake capability. Here, IFNG is linked to Miyoshi myopathy.