FGF21 and metabolic dysfunction-associated steatotic liver disease: These revealed that both NAFLD activity and liver fibrosis were associated with both CD36hi ResKCs, CD36hi MoKCs, and CD9hi MoKCs (Figure 6—figure supplement 2A-D), indicating that FGF21 likely improves liver fibrosis by reducing these lipid- and scar-associated macrophages.