TRPM3 and developmental and epileptic encephalopathy: Recently, de novo variants in TRPM3 were reported in patients with developmental and epileptic encephalopathy (DEE), including 16 patients with the recurrent missense variant p.Val1002Met and two additional patients with the variants p.Pro1102Gln and p.Ser1367Thr, respectively (de Sainte Agathe et al., 2020; Dyment et al., 2019; Gauthier et al., 2021; Kang et al., 2021; Lines et al., 2022; see results and Figure 1 for further discussion and details on numbering of TRPM3 variants).