PRL and brain neoplasm: This work was supported by NIH/National Institute of Neurological Disorders and Stroke (NIH/NINDS) grants R37-NS094804, R01-NS105556, R01-NS122536, R01-NS124167, R01-NS122165, and R21-NS123879-01 as well as the Rogel Cancer Center Scholar Award to MGC; NIH/NINDS grants R01-NS076991, R01-NS082311, R01-NS096756, and R01NS122234 and NIH/National Cancer Institute grant R01-CA243916 to PRL; the Department of Neurosurgery, the Pediatric Brain Tumor Foundation, Leah’s Happy Hearts Foundation, Ian’s Friends Foundation, Chad Tough Foundation, and Smiles for Sophie Forever Foundation to MGC and PRL.