Importantly, fewer than 15 FGFR3::TACC3 pediatric gliomas, presenting initially with LGG histological features, have been reported to date, including one case of PLNTY with secondary malignant transformation [1, 6, 12, 17, 18, 20, 23, 25, 28]. This evidence concerns the gene FGFR3 and glioma.