In our series of diffuse gliomas with FGFR3::TACC3 fusion, PFS (p = 0.029) and OS (p = 0.001) were significantly worse in gliomas demonstrating FGFR3(Ex17)::TACC3(Ex11) fusion (Fig. 5e, f). The gene discussed is FGFR3; the disease is glioma.