Whatever the age of patients and location, diffuse gliomas with FGFR3::TACC3 fusion display recurrent pathological features including oligodendroglioma-like cells, branched vessels, often associated with calcifications and CD34 extra-vascular expression associated in some cases with pathological features of glioblastoma (microvascular proliferation and/or necrosis) [6–9, 12, 17, 20, 23, 26]. The gene discussed is TACC3; the disease is oligodendroglioma.