Interestingly, data mining in the COSMIC database revealed that EP300-R1627W was found not only in TCC BCa in our study, but also in B-cell lymphoma, T-cell lymphoma-leukemia, colon adenocarcinoma, endometrial carcinoma, serous carcinoma, malignant melanoma, and gastric adenocarcinoma. Here, EP300 is linked to B-cell non-Hodgkin lymphoma.