UHRF1 and Alzheimer disease: Conversely, and consistent with differences between healthy aged and AD tissues, the reader effector transcript UHRF1 showed significant lower expression in low and mid Braak staging groups compared to Braak V–VI late stages in the STG (H = 7.9, p = 0.02; post hoc between stages 0–II and V–VI, p = 0.02; post hoc between stages III–IV and V–VI, p = 0.01).