qRT-PCR performed in n = 23 ACC samples (patients’ characteristics in Table 1) showed a higher expression of CA9 in more advanced tumors (n = 14 ACC stage III–IV) than in lower stage samples (n = 9 ACC stage I–II), while CA3 showed an opposite trend, with a significantly higher gene expression in stage I–II vs. more advanced stages. The gene discussed is CA9; the disease is adrenal cortex carcinoma.