MAPT and Alzheimer disease: Assuming, after even longer incubation periods, that such recipients of amyloid-β and tau-contaminated cadaver-derived material also develop a tauopathy in addition to the widespread amyloid-β pathology, thereby meeting the full neuropathological criteria for AD, this would indicate that AD can also result from such iatrogenic exposure to proteopathic seeds and could be considered a prion disease3,15.