USP19 and breast cancer: Then, we performed IF staining for USP19-CY in two tissue microarrays: one contained 34 pairs of breast cancer tissues and adjacent phenotypically normal tissues that were derived from 34 patients, and the other included breast cancer tissues of different stages (IIA, IIB, IIIA, IIB) and 10 adjacent normal tissues (Fig. 6A, B).