In order to investigate whether NE-treated A549/H3122 medium affects CD8+ T-cell migration in vitro, supernatants of NE-treated tumour cells (after 24 h) were loaded into the down wells of a 0.3 μm transwell plate to attract CD8+ T-cell migration, which showed that NE-treated tumour cell supernatants significantly reduced CD8+ T-cell migration (Fig. 2h). The gene discussed is CD8A; the disease is neoplasm.