EGR1 and inflammatory skin disease: Their pathogenesis consistently involves an inflammatory and proliferative component, coordinated by EGR-134; (b) skin inflammatory disorders, like atopic dermatitis, are present in approximately 10% of children with ASD and are significantly associated with neurodevelopmental disorders36; and (3) EGR-1 is also strongly expressed in the gut epithelium, where it plays a complex role in regulating inflammation and immune interactions between host and microbiote37.