Bifidobacterium may migrate to and colonize colon cancer sites to activate dendritic cells (DCs) via the STING signaling pathway.93 Systemic administration of Bifidobacterium induces intratumoral accumulation and alters the response to anti-CD47 immunotherapy in a STING-dependent manner. The gene discussed is STING1; the disease is malignant colon neoplasm.