On the basis of univariate analysis, although a significantly higher proportion of dyslipidemia was observed in the high-titer anti–SARS-CoV-2 S Ab group, the IFN-λ3 value and the proportion of pneumonia were significantly higher in the high-titer anti–SARS-CoV-2 S Ab group. This evidence concerns the gene IFNL3 and metabolic syndrome.