Based on a univariate analysis, the percentage of hypertension, pneumonia upon admission, aspiration pneumonia upon admission, and do not intubate cases, as well as the values for age, C-reactive protein, lactate dehydrogenase, ferritin, IFN-λ3, and D-dimer, were significantly higher in the oxygen-requiring group than in the oxygen-nonrequiring group. The gene discussed is IFNL3; the disease is aspiration pneumonitis.