To assess whether endogenous PGE2 participates in nephron regeneration after AKI, we intraperitoneally injected indomethacin (Indo, 200 μM, 10 μL per fish), an inhibitor of both Cox1 and Cox2, at 2, 4, and 6 dpi (Poureetezadi et al., 2016). The gene discussed is PTGS2; the disease is acute kidney injury.