As PD and DLB share the same pathologic basis, I-123-FP-CIT has shown similar value in the diagnosis of DLB, with a diagnostic accuracy around 90% in discriminating from other dementia syndromes; however, DAT imaging is not reliable for discriminating DLB from PD-related MCI or dementia [115, 116]. This evidence concerns the gene SLC6A3 and Lewy body dementia.