While ~30% of genes up-regulated with infection (160 genes) were shared between the lean and obese groups (Figure 2C), the fold change of several of these genes involved in myeloid cell activation (CSF2, CSF3, CCR7) and cytokine signaling (IL6, IL23A, IL10, IL12B, CCL2, CCL3, CCL4, CCL8, CCL20) was lower in the obese group (Figure 2D). The gene discussed is CCL2; the disease is infection.