Moreover, MET could inhibit cell proliferation, migration, and cancer stem cell (CSC) population in 5‐FU‐resistant SNU‐C5 CRC cell line, which was mediated by the activation of AMP‐activated protein kinase (AMPK) and suppression of DNA replication, and NF‐κB pathway.16 Here, NFKB1 is linked to colorectal carcinoma.