PDGFRB and ischemic stroke: Three days post-reperfusion, the distribution of PDGFR-β and collagen IV was overlapping within most cortical blood vessels and within the leptomeninges (Figures 3I–P), consistent with previous studies showing the increased expression of vascular collagen IV after ischemic stroke (Ji and Tsirka, 2012; Hawkes et al., 2013; Michalski et al., 2020).