IL-18 and IL-6, but not other NRLP3 related mediators, were higher expressed in EAT, compared to PAT and SAT in our non-obese CHD population, and the EAT IL-18 expression correlated inversely with IL-12 and the presence of macrophages, T-cells and endothelial cells, suggesting either other sources or an anti-inflammatory state of the tissue. Here, IL6 is linked to coronary artery disorder.