The comparison between the SARS-CoV-2 group and the control group regarding the ACE gene allelic variants revealed that the D/D variant was significantly detected in the COVID-19 patients compared to the control subjects (53% and 29%, respectively), whereas the I/I variant was significantly detected in the control subjects compared to the COVID-19 patients (53% and 20%, respectively) (p = 0.004), as shown in Figure 3. The gene discussed is ACE; the disease is COVID-19.