Our previous reports demonstrated that oral administration of pemafibrate could prevent pathological retinal neovascularization via decreasing Vegf mRNA expression and hypoxia-inducible factor-1 α (HIF-1 α; one of the master regulatory transcription factors for VEGF in the body including the eye (Ahluwalia & Tarnawski, 2012; Lee et al., 2022a)) protein immunoreactivity in a murine model of oxygen-induced retinopathy (Tomita et al., 2019). Here, VEGFA is linked to retinal disorder.