The relationship of CMTM6 with prognosis in lung cancer is still controversial; Koh et al. (2019) and Zugazagoitia et al. (2019) demonstrated that CMTM6 cannot be an independent risk factor for predicting lung cancer occurrence, while Wang et al. (2020a) reported that LUAD patients with high CMTM6 expression have a better prognosis. Here, CMTM6 is linked to lung cancer.