Immunohistochemical quantitative evaluation and analysis of IL-6 and RANKL expression in the peri-implant bone tissue showed that IL-6 expression in the peri-implantitis group was significantly higher than that in the control and the peri-implantitis+LMT-28 treatment groups (p < 0.05), while there was no significant difference in IL-6 expression between the peri-implantitis+LMT-28 group and the control group (p > 0.05, Figures 10(a)–10(c) and 10(g)). This evidence concerns the gene TNFSF11 and Peri-Implantitis.