Studies have shown that lactate has multifactorial roles in tumorigenesis, functioning as a signaling molecule for tumor angiogenesis and contributing to tumor inflammation and growth by attracting macrophages that then secrete cytokines such as IL-23/IL-17 and growth factors (Shime et al., 2008; Sonveaux et al., 2012; Végran et al., 2011). This evidence concerns the gene IL17A and neoplasm.