While in presurgical assessments of epilepsy and neuro-oncology, combined functional imaging (fMRI-EEG coregistration) is routinely used, the use of multimodal neuroimaging in late-onset AD, especially fMRI and molecular brain mapping of amyloid and tau using PET, is still far from widespread clinical implementation, partly due to the cost and complexity of these techniques. Here, MAPT is linked to Alzheimer disease.