APOE and Stroke: Although in the entire cohort, we did not observe an increased risk of 3-month unfavorable outcome (mRS ≥ 2) in patients with high quartile (Q2-4) of NLR, as compared with patients in Q1 (p for trend = 0.137), we observed differences in the relationship between NLR and unfavorable stroke outcome by APOE ε4 status.