APOE and atrial fibrillation: As shown in Table 3, compared with APOE non-ε4 carriers, APOE ε4 carriers were strongly associated with poor functional outcome (OR = 4.62, 95% CI 3.51–6.09, p < 0.001) overall after adjustment for age, gender, smoking, baseline NIHSS score, LDL level, atrial fibrillation, NLR and homocysteine.