Noteworthy, the SARA has been shown to reflect progression in hereditary ataxias such as SCA1 [58–60], SCA2 [58, 60], SCA3 [58, 60], SCA6 [60], FRDA [61], and even in pre-symptomatic SCA1 carriers [62]. The gene discussed is ATXN3; the disease is hereditary ataxia.